For example:
If your T-case was centred, but with the diff 300 mm lower (at full droop) your total offset is 300 mm.
If you T-case is 150 mm offset, and the diff is 300 mm lower, then your total offset is 335 mm.
If we (willy nilly) assume that your drive shaft is 800 mm long (uj centre to uj centre) then your angle for each uj goes from 10.3 degrees to 11.4 degrees.
Now that's not insignificant by any means, but for the number of K's your doing, the reduced life isn't going to bother you.
There are a couple of winch trucks in Taupo that have run the Prado case with Saf diff for years. That's also how I'm building mine.
Note, I've assumed your flanges are parallel when I stated those angles. At full droop my flanges are not parallel, or even close, and I'm a little worried about it. But if I never finish it, it won't break!

